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Anavex Life Sciences, AVXL, Profile, Summary

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Anavex Life Sciences |AVXL | Profile

Anavex Life Sciences Corp. is a biopharmaceutical company engaged in the discovery and development of new drugs for the treatment of neurological diseases and cancer, utilizing its proprietary drug discovery SIGMACEPTOR™ platform. The Anavex portfolio comprises novel, wholly owned sigma receptor agonists and antagonists. The company’s lead drug candidate for Alzheimer’s Disease (AD), ANAVEX 2-73, has successfully completed a Phase 1 single ascending dose (SAD) clinical trial. The company has also started scale-up manufacturing for ANAVEX 1-41, its second lead compound, targeting depression and AD. With sufficient quantities of ANAVEX 1-41 in hand, the company will be in a position to advance the program and begin preclinical studies on large animals in the near term.

Neurological diseases (CNS): Anavex SIGMACEPTOR™-N program involves the discovery and development of original drug candidates, targeting neurological diseases such as Alzheimer’s disease, epilepsy, and depression. The company’s lead drug candidates exhibit high affinity and selectivity to sigma receptors and also synergistic action with other receptors, such as Muscarinic and NMDA, with strong evidence of anti-amnesic, neuroprotective, and anxiolytic properties.

Oncology: Anavex SIGMACEPTOR™-C program involves the discovery and development of original drug candidates targeting cancer. The company’s lead drug candidates exhibit high affinity to sigma receptors with strong evidence for selective apoptosis of cancerous cells, without affecting healthy cells, anti-metastatic and low toxicity properties in various types of cancer such as melanoma, prostate and pancreas, and neuropathic pain.

In addition, several series of sigma ligands currently at different stages of development, target stroke, diabetes, multiple sclerosis and Parkinson’s disease.

The Pipe Line

Anavex’s lead drug candidate ANAVEX 2-73 -targeting Alzheimer’s Disease- is in Phase 1 clinical trials. The company has also initiated scale-up manufacturing of ANAVEX 1-41 targeting a range of important CNS disorders, including depression and Alzheimer’s Disease. Three more of its compounds (for malignant melanoma, prostatic cancer and epilepsy) are expected to reach final preclinical stages in the near term.

Other early-stage preclinical research (see diagram) involves drug candidates that target diseases like depression, neuropathic pain and various types of cancer.

Source: Anavex, OxBridge Research, Daily Stock Deals

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Fuse Science, DROP, Profile, Sports Medicine, Health Supplements, Energy Drinks

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DROP, Fuse Science

Fuse Science, DROP, Profile, Summary

Fuse Science (DROP) is a consumer products company, developed an alternative delivery systems with applications in the sports nutrition and medical fields. Its delivery systems include sublingual and transdermal delivery technologies that enable energy, medicines, vitamins, and minerals to bypass the gastrointestinal tract and enter the blood stream directly.

The company offers EnerJel to address muscle fatigue and soreness, before, during, and after physical activity. It also provides drop products, including PowerFuse, an energy formulation in a concentrated drop, as well as ElectroFuse, an electrolyte formula in a concentrated drop.

Fuse focus provides revolutionary energy and body replenishment products that combine cutting-edge body delivery technology with two proprietary formulas for powering professional athletes and weekend warriors. Utilizing our unique, bonding technology, Fuse Science has a unique electrolyte and energy delivery system for consumers ranging from the serious athletes to working mothers.

A combination of patent pending technology and unique ingredients has resulted in achievement of superior cosemtic, consumable, transdermal and sublinguall delivery of nutraceuticals and pharmaceuticals. This unique delivery system has allowed for increased absorption of encapsulated nutrients across the epidermis and oral mucosa in our transdermal and sublingual formulations.

DROP, Sports Science

ENERJEL™
Innovative Topical Muscle & Joint Rub from Fuse Science

ENERJEL™ is Fuse Science Inc.’s first innovative, topical product which utilizes elements of their cutting edge delivery system. The proprietary formulation helps fatigued muscles feel energized. ENERJEL™ is applied topically to deliver sustained relief and an energized feeling.

  • ENERJEL’s™ proprietary formulation helps fatigued muscles feel energized.
  • Powered By Fuse™ and made from all natural ingredients, ENERJEL™ is applied topically to help deliver a sustained energized feeling to the target area.
  • ENERJEL™ contains all natural ingredients, such as white willow bark and caffeine

Sources: company, OxBridge Research, Daily Stock Deals

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we received or expecting compensation from the featured company. Our firm, principals and staff may own/buy/sell/trade stock/securities of this company. Always Read the full Disclosure/Disclaimer. Thanks.